abstract：BACKGROUND:Most reports on thalamic infarcts have focused on clinicoanatomical correlations while the mechanisms of stroke have rarely been investigated. Moreover, most series have included mainly elderly stroke patients, whereas scarce information is available about the etiology of thalamic infarcts in the young. OBJ...

journal_title：European neurology

authors： Pezzini A,Del Zotto E,Archetti S,Albertini A,Gasparotti R,Magoni M,Vignolo LA,Padovani A

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to investigate whether there are clues for a correlation between tumor progression and serum anti-Hu antibody concentration in patients with anti-Hu-associated paraneoplastic neurological syndromes (PNS). 19 patients with anti-Hu-associated PNS were assigned to three groups according to the c...

journal_title：European neurology

authors： Rauer S,Andreou I

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Cardiac myxomas may present clinically with many different features. Since highly effective treatments exist, it is important that they are diagnosed quickly in order to avoid further complications. Our aim was to determine the influence of neurological presentation in diagnosis and prognosis of car...

journal_title：European neurology

authors： Alvarez-Sabín J,Lozano M,Sastre-Garriga J,Montoyo J,Murtra M,Abilleira S,Codina A

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:To evaluate the role of computed tomography angiography (CTA) and magnetic resonance angiography (MRA) in the quantification of atherosclerotic stenosis of carotid artery bifurcation in comparison with digital substraction angiography (DSA) and Doppler sonography (DS). MATERIALS AND METHODS:Twenty-five patient...

journal_title：European neurology

authors： Binaghi S,Maeder P,Uské A,Meuwly JY,Devuyst G,Meuli RA

更新日期：2001-01-01 00:00:00

abstract：:Temporal arteritis (TA) is a vasculitis involving mainly cranial branches of the aorta that can lead to ischemic complications such as amaurosis or ischemic stroke. Increment in the platelet count has been described in the acute period of the disease. We studied retrospectively the platelet count in patients with TA, ...

journal_title：European neurology

authors： Gonzalez-Alegre P,Ruiz-Lopez AD,Abarca-Costalago M,Gonzalez-Santos P

更新日期：2001-01-01 00:00:00

abstract：:Patients suffering from migraine, tension-type headache (TTH), or combined headache (CH) are at risk of developing drug-induced headache (DIH) due to regular use of analgesics, ergot alkaloids, and triptans. The aim of our study was to determine (1) the clinical features of DIH, (2) the outcome of withdrawal therapy u...

journal_title：European neurology

authors： Fritsche G,Eberl A,Katsarava Z,Limmroth V,Diener HC

更新日期：2001-01-01 00:00:00

abstract：:Current treatment options for restless legs syndrome (RLS), based on the American Academy of Sleep Medicine practice parameters, favor dopaminergic agents. The drug of first choice is levodopa, which is now licensed for RLS in two European countries. However, the short duration of action and augmentation of symptoms u...

journal_title：European neurology

authors： Stiasny K

更新日期：2001-01-01 00:00:00

abstract：:Cavernomas are vascular malformations mostly observed in the central nervous system. They occur in sporadic and familial forms. Familial forms are characterized by the presence of multiple lesions, an autosomal dominant pattern of inheritance and possible de novo lesions. We report two sporadic cases whose follow-up s...

journal_title：European neurology

authors： Labauge P,Brunereau L,Coubes P,Clanet M,Tannier C,Laberge S,Lévy C

更新日期：2001-01-01 00:00:00

abstract：:It is generally believed that a homonymous defect of macular vision (HMV) is caused by a small lesion restricted to the occipital lobe tip and rarely results from ischemic stroke. The incidence of HMV was studied retrospectively in 54 patients with infarction of the posterior cerebral artery territory who underwent Go...

journal_title：European neurology

authors： Isa K,Miyashita K,Yanagimoto S,Nagatsuka K,Naritomi H

更新日期：2001-01-01 00:00:00

abstract：:Automatic analysis of EMG (T/A analysis) and invasive muscle fiber conduction velocity in situ (MFCV) were performed in 15 patients after traumatic lesions of the knee and immobilization with quadriceps atrophy. T/A analysis showed transient reduced number of turns, consistent with inhibition of quadriceps motoneurons...

journal_title：European neurology

authors： Cruz-Martínez A,Ramírez A,Arpa J

更新日期：2000-01-01 00:00:00

abstract：:The role of genetics in Parkinson's disease (PD), previously controversial, is now documented by several studies. A major breakthrough has been the discovery of two single-gene defects in familial PD. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein gene has been ...

journal_title：European neurology

authors： Hu CJ,Sung SM,Liu HC,Lee CC,Tsai CH,Chang JG

更新日期：2000-01-01 00:00:00

abstract：:The purpose of this study was to estimate the risk factors, early course, outcome and neuroimaging patterns in primary intracerebral hemorrhages (PIH). Using the Besançon Stroke Registry, 350 patients with first PIH documented by computed tomography (CT) between 1987 and 1993 were included in the present study. Patien...

journal_title：European neurology

authors： Tatu L,Moulin T,El Mohamad R,Vuillier F,Rumbach L,Czorny A

更新日期：2000-01-01 00:00:00

abstract：:This study investigates the remote effects of botulinum toxin injections by examining the motor unit architecture of noninjected distant muscles. In 21 dystonia patients treated with botulinum toxin (n = 11, mean cumulative dose = 815 mU; n = 10, mean cumulative dose = 7,207 mU) and 10 control individuals, a blinded s...

journal_title：European neurology

authors： Fertl E,Schnider P,Schneider B,Auff E

更新日期：2000-01-01 00:00:00

abstract：:Bilateral paramedian thalamic infarcts are characterised initially by the association of acute vigilance disorders and vertical gaze palsy, followed by persisting dementia with severe mnemic disturbance, global aspontaneity and apathy. We describe a patient with a dramatic neuropsychological recovery, confirmed by tes...

journal_title：European neurology

authors： Krolak-Salmon P,Croisile B,Houzard C,Setiey A,Girard-Madoux P,Vighetto A

更新日期：2000-01-01 00:00:00

abstract：:Five patients with clinical features of corticobasal degeneration (CBD) were studied with PET imaging. The main clinical findings included a unilateral extrapyramidal motor disorder, without significant response to levodopa, as well as clumsiness, dysarthria, apraxia and a clear asymmetry of neurological signs. PET st...

journal_title：European neurology

authors： Lutte I,Laterre C,Bodart JM,De Volder A

更新日期：2000-01-01 00:00:00

abstract：:In the fast moving field of muscular dystrophy, therapeutic matters are now high on the agenda. Despite little progress made in the understanding of the exact pathogenesis, hopes have been raised with the advent of molecular medicine applied to such disorders. A constellation of techniques or therapeutic solutions are...

journal_title：European neurology

authors： Urtizberea JA

更新日期：2000-01-01 00:00:00

abstract：:Diplopia, blurred vision and colour disturbances are well-known side effects associated with anti-epileptic drugs (AEDs). Farnsworth-Munsell 100-hue colour test (F-100) is an accepted and sensitive tool to detect changes in colour perception. To determine the impact of AEDs upon colour vision, we evaluated 37 consecut...

journal_title：European neurology

authors： López L,Thomson A,Rabinowicz AL

更新日期：1999-01-01 00:00:00

abstract：:This retrospective study aims to assess cognitive involvement in pre-AIDS, not drug abuser subjects and to determine whether CD4 status or disease stage best correlates with cognitive changes that may portend development of ADC. 328 cases were analyzed. No differences in psychometric performance in relation to CDC sta...

journal_title：European neurology

authors： Grassi MP,Perin C,Borella M,Mangoni A

更新日期：1999-01-01 00:00:00

abstract：:To elucidate the clinical characteristics of aged patients with Becker muscular dystrophy (BMD), 4 patients with this disease who were over 50 years were examined. The ages at onset in all patients were later than 30 years. All were proven to have a deletion around exons 45-55 of the Duchenne muscular dystrophy (DMD) ...

journal_title：European neurology

authors： Yazaki M,Yoshida K,Nakamura A,Koyama J,Nanba T,Ohori N,Ikeda S

更新日期：1999-01-01 00:00:00

abstract：:The role of genetics in Parkinson's disease (PD), previously controversial, is now supported by several studies. A major breakthrough has been the discovery of a single gene defect in familial Parkinson's disease. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein g...

journal_title：European neurology

authors： Hu CJ,Sung SM,Liu H,Chang JG

更新日期：1999-01-01 00:00:00

abstract：:The aim of the present work was to evaluate verbal working memory in patients affected by Parkinson's disease (PD). In particular, tests that explore the functionality of the Articulatory Loop and of the Central Executive during verbal tasks were given. PD patients displayed normal phonological similarity, word length...

journal_title：European neurology

authors： Graceffa AM,Carlesimo GA,Peppe A,Caltagirone C

更新日期：1999-01-01 00:00:00

abstract：:Magnetic resonance imaging and angiography is the technique of choice in the diagnosis and follow-up of cerebral venous thrombosis: Thrombosis appears as an absence of flow void on spin echo images and lack of signal in angiographic techniques. The thrombus signal intensity is different on T1 and T2 spin echo weighted...

journal_title：European neurology

authors： Bianchi D,Maeder P,Bogousslavsky J,Schnyder P,Meuli RA

更新日期：1998-11-01 00:00:00

abstract：:The neuropathological diagnosis of Alzheimer's disease relies on the presence of both neurofibrillary tangles and senile plaques. The number of neurofibrillary tangles is tightly linked to the degree of dementia, suggesting that the formation of neurofibrillary tangles more directly correlates with neuronal dysfunctio...

journal_title：European neurology

authors： Brion JP

更新日期：1998-10-01 00:00:00

abstract：:Neuropathological changes such as dystrophic neurites and the presence of abnormal tau protein in the olfactory system, including primary sensory cells and nerve fibres have previously been demonstrated in nasal mucosa tissue of patients with Alzheimer's disease (AD). These changes were detected in autopsy-derived mat...

journal_title：European neurology

authors： Hock C,Golombowski S,Müller-Spahn F,Peschel O,Riederer A,Probst A,Mandelkow E,Unger J

更新日期：1998-07-01 00:00:00

abstract：:Although many studies have been performed on nervous tissue pathology in Guillain-Barré syndrome (GBS), much less is known about pathological changes in skeletal muscle in this disorder. We have studied muscle biopsies from 5 patients with GBS, 5 patients with amyotrophic lateral sclerosis (control A), and 5 patients ...

journal_title：European neurology

authors： Ono S,Inoue K,Munakata S,Nagao K,Shimizu N

更新日期：1998-01-01 00:00:00

abstract：:So-called apraxia of eyelid opening (scAEO) has been described chiefly in the context of extrapyramidal disorders. We described 10 new patients with scAEO developing in the absence of any other CNS sign and reviewed the 11 cases with isolated scAEO reported in the literature. Combining our patients and those from the ...

journal_title：European neurology

authors： Defazio G,Livrea P,Lamberti P,De Salvia R,Laddomada G,Giorelli M,Ferrari E

更新日期：1998-01-01 00:00:00

abstract：:Transient ischemic attacks (TIAs) are warning episodes predicting that such patients are at high risk for stroke which potentially could be life-threatening or leave an individual with substantial disability. TIAs result from large or small vessel disease, cardiogenic embolic events and hematological abnormalities. Th...

journal_title：European neurology

authors： Anwer UE

更新日期：1998-01-01 00:00:00

abstract：:Hypertrophic changes in the inferior olivary nuclei have been occasionally described in patients with progressive supranuclear palsy (PSP). To elucidate the incidence of olivary hypertrophy, we investigated morphologically the olives and their associated pathways in 20 autopsied cases: 11 cases of PSP, 3 cases of Mach...

journal_title：European neurology

authors： Hanihara T,Amano N,Takahashi T,Itoh Y,Yagishita S

更新日期：1998-01-01 00:00:00

abstract：:Many gadolinium-enhanced magnetic resonance imaging (MRI) studies focusing on the anatomy and pathology of the 7th cranial nerve have already been published. However, only scattered cases of herpes zoster oticus (HZO) have been described and only the MRI appearance of the soft temporal bone structures has been reporte...

journal_title：European neurology

authors： Berrettini S,Bianchi MC,Segnini G,Sellari-Franceschini S,Bruschini P,Montanaro D

更新日期：1998-01-01 00:00:00

abstract：:Dementia is one of the most common organic mental syndromes, usually caused by Alzheimer's disease (AD) or vascular dementia (VD) or both. Regarding AD we review the state or the art of the cholinergic approach and discuss some future options regarding preventive and nonsymptomatic strategies. Therapy for VD will cons...

journal_title：European neurology

authors： Scheltens P,van Gool WA

更新日期：1997-01-01 00:00:00

abstract：:Bilateral choroid plexus papillomas, or villous hypertrophy of the choroid plexus, is a very rare entity that presents serious therapeutical problems in the management of secondary oversecretive hydrocephalus. The authors report the cases of 2 infants affected by this condition, and cured with removal of the lateral v...

journal_title：European neurology

authors： Di Rocco C,Iannelli A

更新日期：1997-01-01 00:00:00

abstract：:18F-Dopa positron emission tomography (PET) provides a sensitive means of quantitating the loss of nigrostriatal dopaminergic fibres in Parkinson's disease and so can be used to diagnose its presence and to objectively follow the rate of disease progression. It can also be used, in principle, to determine the efficacy...

journal_title：European neurology

authors： Brooks DJ

更新日期：1997-01-01 00:00:00

abstract：:We report a short-term double-blind, crossover study of CoQ10 in 8 patients with mitochondrial encephalomyopathies. Four patients had myoclonus epilepsy with ragged-red fibers syndrome, 3 had mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes syndrome, and 1 had chronic progressive extern...

journal_title：European neurology

authors： Chen RS,Huang CC,Chu NS

更新日期：1997-01-01 00:00:00

abstract：:To clarify the function of human atrial natriuretic peptide (hANP) in the cerebrospinal fluid (CSF), we examined hANP levels in the CSF of patients with various neurological diseases. The subjects were 16 controls without neurological disease and 45 patients with neurological disease. The 45 patients with neurological...

journal_title：European neurology

authors： Yamasaki H,Sugino M,Ohsawa N

更新日期：1997-01-01 00:00:00

abstract：:Mitochondrial abnormalities and effectiveness of replacement therapy were examined in a murine model of systemic carnitine deficiency, namely the juvenile visceral steatosis (JVS) mouse. Homozygous JVS mice revealed severe lipid deposition and abnormal mitochondria in liver, heart, skeletal muscle, and kidney, but the...

journal_title：European neurology

authors： Kaido M,Fujimura H,Ono A,Toyooka K,Yoshikawa H,Nishimura T,Ozaki K,Narama I,Kuwajima M

更新日期：1997-01-01 00:00:00

abstract：:We report a laser microprobe mass analysis of aluminum and iron content in the hippocampus and in the inferior temporal cortex in 2 cases of dementia pugilistica (DP), 4 cases of Alzheimer's disease (AD), and 3 controls. There was a predominant accumulation of Al and Fe within neurofibrillary tangles (NFT) in both DP ...

journal_title：European neurology

authors： Bouras C,Giannakopoulos P,Good PF,Hsu A,Hof PR,Perl DP

更新日期：1997-01-01 00:00:00

abstract：:QTc intervals were measured in 30 patients with Parkinson's disease and 30 healthy control subjects. The mean value of QTc intervals in patients with Parkinson's disease significantly exceeded that of healthy controls (418 +/- 14 ms vs. 403 +/- 18 ms). Prolongation of the QTc interval was unrelated to the administrati...

journal_title：European neurology

authors： Oka H,Mochio S,Sato H,Katayama K

更新日期：1997-01-01 00:00:00

abstract：:Autosomal dominant Parkinson's disease in 5 generations of a family living in Sagamihara City is reported. Clinical features of this family did not differ from common PD, however, neuropathological findings were different from PD. In autopsied cases, the loss of melanin-containing cells was mild to moderate, and the n...

journal_title：European neurology

authors： Hasegawa K,Kowa H

更新日期：1997-01-01 00:00:00

abstract：:The aim of this study was to investigate whether the side and location of single small infarcts (< or = 3 cm) in the corona radiata (28 patients) and pontine base (36 patients) influence the incidence of contralateral upper or lower limb paresis and dysarthria. While the severity of contralateral limb paresis was not ...

journal_title：European neurology

authors： Tohgi H,Takahashi S,Takahashi H,Tamura K,Yonezawa H

更新日期：1996-01-01 00:00:00

abstract：:This study aimed at examining correlations between quantitative REM sleep EEG, regional cerebral blood flow measured by single photon emission computerized tomography (SPECT) and global cognitive functioning in nine patients with mild to moderate Alzheimer's disease. REM sleep EEG was not correlated with SPECT measure...

journal_title：European neurology

authors： Montplaisir J,Petit D,McNamara D,Gauthier S

更新日期：1996-01-01 00:00:00